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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T82502 Efaprinermin alfa

OMP-336B11

Efaprinermin alfa (OMP-336B11),一种人源化单克隆抗体,靶向TNFRSF18。该化合物为GITR配体-Fc融合蛋白。

化合物

Efaprinermin alfa
Cat.No: T82502
Synonym: OMP-336B11
Target:
Cat. No. Product Name Species Expression System
TMPK-01064 GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)

GITRL,GITR Ligand,TL6,TNFSF18,AIT...

Mouse HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is ...
TMPK-00053 GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)

AITRL,TNFSF18,TL6,GITR Ligand,GITR

Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecula...
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

TL6,GITR Ligand,TNFSF18,AITRL,GITR

Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with...
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)

GITRL,TNFSF18,Activation-inducible TNF-related ...

Cynomolgus HEK293 Cells
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ...

重组蛋白

GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01064
Species: Mouse
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00053
Species: Human
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00054
Species: Human
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00432
Species: Cynomolgus
Expression System: HEK293 Cells
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